Membrane damage thresholds for pulsed or continuous ultrasound in phagocytic cells loaded with contrast agent gas bodies.

@article{Miller2004MembraneDT,
  title={Membrane damage thresholds for pulsed or continuous ultrasound in phagocytic cells loaded with contrast agent gas bodies.},
  author={Douglas L. Miller and Chunyan Dou},
  journal={Ultrasound in medicine & biology},
  year={2004},
  volume={30 3},
  pages={405-11}
}
Cell membrane damage induced by pulsed or continuous ultrasound (US) activation of attached contrast agent gas bodies was examined in an in vitro model system. Monolayers of mouse macrophage-like cells were cultured on the inside of one window of an exposure chamber. The monolayers were incubated with Optison (Amersham Health Inc., Princeton, NJ) or Definity (Bristol-Myers Squib Medical Imaging, North Billerica, MA) and then rinsed to remove unattached gas bodies. A 3.5-MHz focused transducer… CONTINUE READING