Membrane currents underlying delayed rectification and pace-maker activity in frog atrial muscle.

@article{Brown1969MembraneCU,
  title={Membrane currents underlying delayed rectification and pace-maker activity in frog atrial muscle.},
  author={Hilary F. Brown and Stephen Noble},
  journal={The Journal of physiology},
  year={1969},
  volume={204 3},
  pages={717-36}
}
1. A double sucrose gap method has been used to polarize and voltage clamp frog atrial muscle strips.2. In response to steady depolarizing currents, normally quiescent strips often show pace-maker activity, and long lasting depolarization occurs when the current is terminated.3. Voltage clamp experiments reveal the presence of two current components underlying delayed rectification.4. The first of these components has a time constant which varies with potential and is approximately 500 msec at… CONTINUE READING

From This Paper

Topics from this paper.
25 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

Similar Papers

Loading similar papers…