Membrane currents in the rabbit atrioventricular node cell

  title={Membrane currents in the rabbit atrioventricular node cell},
  author={Shinichiro Kokubun and Masao Nishimura and Akinori Noma and Hiroshi Irisawa},
  journal={Pfl{\"u}gers Archiv},
The rabbit A-V node was dissected into pieces (0.2×0.2×0.2 mm) smaller than its space constant of 692±96 μm (n=5). These small specimens showed spontaneous action potentials whose configurations were similar to those of large specimens before dissection. The membrane time constant was 21.5±1.5 ms (n=5). Voltage clamp experiments were performed on the above specimens using the two-microelectrode technique. On depolarization from the holding potential of −40 mV to various potential levels a… CONTINUE READING


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