Membrane currents in cultured human intestinal smooth muscle cells.

@article{Zholos2000MembraneCI,
  title={Membrane currents in cultured human intestinal smooth muscle cells.},
  author={Alexander V. Zholos and Claire Fenech and Sally A Prestwich and Thomas B. Bolton},
  journal={The Journal of physiology},
  year={2000},
  volume={528 Pt 3},
  pages={521-37}
}
Using whole-cell patch-clamp recording techniques, we have examined voltage-gated ion currents in a cultured human intestinal smooth muscle cell line (HISM). Experiments were performed at room temperature on cells after passages 16 and 17. Two major components of the whole-cell current were a tetraethylammonium-sensitive (IC50 = 9 mM), iberiotoxin-resistant… CONTINUE READING