Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.

Abstract

In recent years, advances in the humanized mouse system have led to significantly increased levels of human hematopoietic stem cell (HSC) engraftment. The remaining limitations in human HSC engraftment and function include lymphoid-skewed differentiation and inefficient myeloid development in the recipients. Limited human HSC function may partially be… (More)
DOI: 10.1182/blood-2011-05-353201

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