Membrane binding and bending in Ebola VP40 assembly and egress

@inproceedings{Stahelin2014MembraneBA,
  title={Membrane binding and bending in Ebola VP40 assembly and egress},
  author={Robert V. Stahelin},
  booktitle={Front. Microbiol.},
  year={2014}
}
Lipid-enveloped viruses contain a lipid bilayer coat that protects their genome and helps to facilitate entry into the host cell. Filoviruses are lipid-enveloped viruses that have up to 90% clinical fatality and include Marbug (MARV) and Ebola (EBOV). These pleomorphic filamentous viruses enter the host cell through their membrane-embedded glycoprotein and then replicate using just seven genes encoded in their negative-sense RNA genome. EBOV budding occurs from the inner leaflet of the plasma… CONTINUE READING

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