Membrane active phenylalanine conjugated lipophilic norspermidine derivatives with selective antibacterial activity.

@article{Konai2014MembraneAP,
  title={Membrane active phenylalanine conjugated lipophilic norspermidine derivatives with selective antibacterial activity.},
  author={Mohini Mohan Konai and Chandradhish Ghosh and Venkateswarlu Yarlagadda and Sandip Samaddar and Jayanta Haldar},
  journal={Journal of medicinal chemistry},
  year={2014},
  volume={57 22},
  pages={9409-23}
}
Natural and synthetic membrane active antibacterial agents offer hope as potential solutions to the problem of bacterial resistance as the membrane-active nature imparts low propensity for the development of resistance. In this report norspermidine based antibacterial molecules were developed that displayed excellent antibacterial activity against various wild-type bacteria (Gram-positive and Gram-negative) and drug-resistant bacteria (methicillin-resistant Staphylococcus aureus, vancomycin… CONTINUE READING
Highly Cited
This paper has 18 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS