Membrane Tension in Rapidly Moving Cells Is Determined by Cytoskeletal Forces

  title={Membrane Tension in Rapidly Moving Cells Is Determined by Cytoskeletal Forces},
  author={Arnon D. Lieber and Shlomit Yehudai-Resheff and Erin L. Barnhart and Julie A. Theriot and Kinneret Keren},
  journal={Current Biology},
BACKGROUND Membrane tension plays an essential role in cell motility. The load imposed by the tensed membrane restrains actin polymerization, promotes rear retraction, and influences membrane transport. Moreover, membrane tension is crucial for large-scale coordination of cell boundary dynamics. Despite its importance, little is known about how membrane tension is set and regulated in cells. The prevailing hypothesis is that membrane tension is largely controlled by membrane-cytoskeleton… CONTINUE READING
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