Membrane Structure: Some General Principles

  title={Membrane Structure: Some General Principles},
  author={Mark S. Bretscher},
  pages={622 - 629}
  • M. Bretscher
  • Published 17 August 1973
  • Biology, Chemistry
  • Science
The arrangement of lipids and some proteins in the erythrocyte membrane has been discussed. The conclusions from this are listed here as a set of general guidelines for the structure of membranes of higher organisms: some of these rules may be wrong. But at this stage it seems useful to sharpen our thoughts in this way and thereby focus attention on various specific points. 1) The basis of a membrane is a lipid bilayer with (i) choline phospholipids and glycolipids in the external half and (ii… 

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