Membrane-Mediated Interactions
@article{Bitbol2018MembraneMediatedI, title={Membrane-Mediated Interactions}, author={Anne-Florence Bitbol and Doru Constantin and Jean-Baptiste Fournier}, journal={arXiv: Biological Physics}, year={2018}, pages={311-350} }
Interactions mediated by the cell membrane between inclusions, such as membrane proteins or antimicrobial peptides, play important roles in their biological activity. They also constitute a fascinating challenge for physicists, since they test the boundaries of our understanding of self-assembled lipid membranes, which are remarkable examples of two-dimensional complex fluids. Inclusions can couple to various degrees of freedom of the membrane, resulting in different types of interactions. In…
4 Citations
Membrane-Mediated Interactions Between Protein Inclusions
- BiologyFrontiers in Molecular Biosciences
- 2021
The membrane-mediated interactions originate from perturbation of lipid membranes by the presence of protein inclusions, and have been the subject of intensive research in membrane biophysics.
Size-dependent aggregation of hydrophobic nanoparticles in lipid membranes.
- BiologyNanoscale
- 2020
It is found that the free energy of dimerization depends strongly on nanoparticle size: the smallest molecules (mimicking C60 fullerene) aggregate only weakly, the largest ones form large three-dimensional aggregates causing major deformations in the host membrane, and the intermediate-sized particles show a tendency to form linear aggregates.
A formula for membrane mediated point particle interactions on near spherical biomembranes
- BiologyInterfaces and Free Boundaries
- 2021
We consider a model of a biomembrane with attached proteins. The membrane is represented by a near spherical continuous surface and attached proteins are described as discrete rigid structures which…
Revealing the Mechanisms of Synergistic Action of Two Magainin Antimicrobial Peptides
- BiologyFrontiers in Medical Technology
- 2020
Detailed dose-response curves, presented here for the first time, show a cooperative behavior for the individual peptides which is much increased when PGLa and magainin are added as equimolar mixture, which can potentially be used to increase the therapeutic window of pharmaceutical formulations.
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