Membrane Fluidity, Invasiveness and Dynamic Phenotype of Metastatic Prostate Cancer Cells after Treatment with Soy Isoflavones

@article{Ajdanovi2013MembraneFI,
  title={Membrane Fluidity, Invasiveness and Dynamic Phenotype of Metastatic Prostate Cancer Cells after Treatment with Soy Isoflavones},
  author={Vladimir Z. Ajd{\vz}anovi{\'c} and Marija K Moji{\'c} and Danijela Maksimovi{\'c}-Ivani{\'c} and Mirna Z. Bulatovi{\'c} and Sanja Mijatovi{\'c} and Verica Lj. Milo{\vs}evi{\'c} and Ivan Spasojevi{\'c}},
  journal={The Journal of Membrane Biology},
  year={2013},
  volume={246},
  pages={307-314}
}
Soy isoflavones represent hopeful unconventional remedies in the therapy of prostate cancer. The aim of our study was to determine the effects of genistein and daidzein on the parameters that reflect metastatic potential, membrane fluidity, invasiveness and dynamic phenotype in Matrigel of LNCaP and PC-3 prostate cancer cells. Cell viability tests, using a wide range of concentrations of soy isoflavones (6–75 μg/ml for 72 h), were conducted to determine their IC50 concentrations. Electron… CONTINUE READING
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