Membrane Determinants Affect Fibrillation Processes of β-Sheet Charged Peptides.

Assembly of fibrillar peptide structures is dependent both upon their intrinsic propensities toward β-structure formation, as well as on structural modulation by external molecular factors. β-sheet structures may either be designed to form useful assemblies or be the undesired consequence of protein denaturation to toxic amyloid structures in several… CONTINUE READING