Members of the NuRD chromatin remodeling complex interact with AUF1 in developing cortical neurons.

@article{Lee2008MembersOT,
  title={Members of the NuRD chromatin remodeling complex interact with AUF1 in developing cortical neurons.},
  author={Cheol Lee and Andrea B. Gyorgy and Dragan Maric and Navid Sadri and Robert J Schneider and Jeffery L. Barker and M. Lawson and Denes V. Agoston},
  journal={Cerebral cortex},
  year={2008},
  volume={18 12},
  pages={2909-19}
}
Chromatin remodeling plays an important role in coordinating gene expression during cortical development, however the identity of molecular complexes present in differentiating cortical neurons that mediate the process remains poorly understood. The A + U-rich element-binding factor 1 (AUF1) is a known regulator of messenger RNA stability and also acts as a transcription factor upon binding to AT-rich DNA elements. Here we show that AUF1 is specifically expressed in subsets of proliferating… CONTINUE READING