Members of the Meis 1 and Pbx Homeodomain Protein Families Cooperatively Bind a cAMP-responsive Sequence ( CRS 1 ) from Bovine CYP 17 *

@inproceedings{Bischof1998MembersOT,
  title={Members of the Meis 1 and Pbx Homeodomain Protein Families Cooperatively Bind a cAMP-responsive Sequence ( CRS 1 ) from Bovine CYP 17 *},
  author={Larry J. Bischof and Norio Kagawa and John J. Moskow and Yoshitaka Takahashi and Akihiro Iwamatsu and Arthur M. Buchberg and Michael R. Waterman},
  year={1998}
}
The mammalian Pbx homeodomain proteins provide specificity and increased DNA binding affinity to other homeodomain proteins. A cAMP-responsive sequence (CRS1) from bovine CYP17 has previously been shown to be a binding site for Pbx1. A member of a second mammalian homeodomain family, Meis1, is now also demonstrated to be a CRS1-binding protein upon purification using CRS1 affinity chromatography. CRS1 binding complexes from Y1 adrenal cell nuclear extract contain both Pbx1 and Meis1. This is… CONTINUE READING

References

Publications referenced by this paper.

Guidebook to the Homeobox Genes (Duboule, D., ed) pp. 25–71

T. R. Burglin
1994
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Highly Influenced

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