Member of the CREB/ATF protein family, but not CREB alpha plays an active role in BLV tax trans activation in vivo.


The trans activator protein of Bovine Leukaemia Virus (tax) increases the rate of transcription from the virus promoter through 21 bp sequences located in three tandem copies in the virus LTR. Based on data obtained by three different experimental approaches we concluded that the central CRE-like motif found in each of the BLV 21 bp repeats plays an… (More)


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