Memantine in dementia: a review of the current evidence.


INTRODUCTION As the world's population ages, the incidence of Alzheimer's disease (AD) is projected to double every 20 years. Understanding the pathogenesis of AD and developing effective treatments is a public health imperative. Memantine is a low- to moderate-affinity, non-competitive NMDA receptor antagonist that is currently approved for the treatment… (More)
DOI: 10.1517/14656566.2011.558006