Memantine as Adjunctive Therapy in Children Diagnosed With Autistic Spectrum Disorders: An Observation of Initial Clinical Response and Maintenance Tolerability

@article{Chez2007MemantineAA,
  title={Memantine as Adjunctive Therapy in Children Diagnosed With Autistic Spectrum Disorders: An Observation of Initial Clinical Response and Maintenance Tolerability},
  author={Michael G. Chez and Quinn Burton and Timothy Dowling and Min-Te Chang and Pavan Khanna and C. Kramer},
  journal={Journal of Child Neurology},
  year={2007},
  volume={22},
  pages={574 - 579}
}
Autism and Pervasive Developmental Disorder Not Otherwise Specified are common developmental problems often seen by child neurologists. There are currently no cures for these lifelong and socially impairing conditions that affect core domains of human behavior such as language, social interaction, and social awareness. The etiology may be multifactorial and may include autoimmune, genetic, neuroanatomic, and possibly excessive glutaminergic mechanisms. Because memantine is a moderate affinity… 
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