Melting of DNA oligomers: dynamical models and comparison with experimental results.


We compare experimental melting curves of short heterogeneous DNA oligomers with theoretical curves derived from statistical mechanics. Partition functions are computed with the one-dimensional Peyrard-Bishop (PB) Hamiltonian, already used in the study of the melting of long DNA chains. Working with short chains we take into account, in the computations… (More)
DOI: 10.1023/A:1005166612156


  • Presentations referencing similar topics