Meloxicam, 15 mg/day, spares platelet function in healthy volunteers.

  title={Meloxicam, 15 mg/day, spares platelet function in healthy volunteers.},
  author={A de Meijer and H Vollaard and Menno de Metz and Bert W Verbruggen and Christoforos Thomas and Irena Nov{\'a}kov{\`a}},
  journal={Clinical pharmacology and therapeutics},
  volume={66 4},
OBJECTIVE To study the influence of meloxicam, a cyclooxygenase-2 (COX-2) preferential nonsteroidal anti-inflammatory drug, on serum thromboxane and platelet function in healthy volunteers with use of the maximum recommended daily dosage of 15 mg/day. METHODS This study used an open, randomized crossover design. Indomethacin (INN, indometacin) was given as a positive control for nonsteroidal anti-inflammatory drug-induced inhibition of platelet function. The following variables were recorded… CONTINUE READING
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