Melittin: a membrane-active peptide with diverse functions.

  title={Melittin: a membrane-active peptide with diverse functions.},
  author={Hariharasundaram Raghuraman and Amitabha Chattopadhyay},
  journal={Bioscience reports},
  volume={27 4-5},
Melittin is the principal toxic component in the venom of the European honey bee Apis mellifera and is a cationic, hemolytic peptide. It is a small linear peptide composed of 26 amino acid residues in which the amino-terminal region is predominantly hydrophobic whereas the carboxy-terminal region is hydrophilic due to the presence of a stretch of positively charged amino acids. This amphiphilic property of melittin has resulted in melittin being used as a suitable model peptide for monitoring… CONTINUE READING
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