Melatonin treatment in the prevention of postoperative delirium in cardiac surgery patients

  title={Melatonin treatment in the prevention of postoperative delirium in cardiac surgery patients},
  author={Panagiotis Artemiou and Boris Bily and Miroslava Bilecov{\'a}-Rabajdov{\'a} and Franti{\vs}ek Sabol and Pavol Torok and Peter Kolar{\vc}ik and Adri{\'a}n Koles{\'a}r},
  booktitle={Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery},
INTRODUCTION Post-cardiac surgery delirium is a severe complication. The circadian rhythm of melatonin secretion has been shown to be altered postoperatively. AIM OF THE STUDY It was hypothesized that restoring normal sleeping patterns with a substance that is capable of resynchronizing circadian rhythm such as exogenous administration of melatonin may possibly reduce the incidence of postoperative delirium. MATERIAL AND METHODS This paper represents a prospective clinical observational… CONTINUE READING
3 Citations
15 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 15 references

Predisposing and precipitating factors of delirium after cardiac surgery . A prospective observational cohort study

  • U Guenther, N Theuerkauf, +6 authors J Popp
  • Ann Surg
  • 2013

High preoperative plasma neopterin predicts delirium after cardiac surgery in older patients

  • RJ Osse, D Fekkes, JH Tulen, AI Wierdsma, AJ Bogers, RC vanderMast
  • J Am Geriatr Soc
  • 2012

Early postcardiac surgery delirium risk factors

  • J Andrejaitiene, E Sirviskas
  • Perfusion
  • 2011

Incidence and predictors of delirium after cardiac surgery . Results from the IPAC study

  • J Kazmiersky, M Kowman, +8 authors I Kloszewska
  • J Psychom Res
  • 2010

Similar Papers

Loading similar papers…