Melatonin treatment in the prevention of postoperative delirium in cardiac surgery patients

@inproceedings{Artemiou2015MelatoninTI,
  title={Melatonin treatment in the prevention of postoperative delirium in cardiac surgery patients},
  author={Panagiotis Artemiou and Boris Bily and Miroslava Bilecov{\'a}-Rabajdov{\'a} and Franti{\vs}ek Sabol and Pavol Torok and Peter Kolar{\vc}ik and Adri{\'a}n Koles{\'a}r},
  booktitle={Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery},
  year={2015}
}
INTRODUCTION Post-cardiac surgery delirium is a severe complication. The circadian rhythm of melatonin secretion has been shown to be altered postoperatively. AIM OF THE STUDY It was hypothesized that restoring normal sleeping patterns with a substance that is capable of resynchronizing circadian rhythm such as exogenous administration of melatonin may possibly reduce the incidence of postoperative delirium. MATERIAL AND METHODS This paper represents a prospective clinical observational… CONTINUE READING
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