Melatonin rhythms in stroke patients.

  title={Melatonin rhythms in stroke patients.},
  author={Yichayaou Beloosesky and Josef Grinblat and Moshe Laudon and Boris Grosman and Jonathan Y. Streifler and Nava Zisapel},
  journal={Neuroscience letters},
  volume={319 2},
Very little is known regarding melatonin's circadian rhythm in stroke patients. We compared urinary-sulfatoxymelatonin (6-SMT), its major metabolite, in 11 extensive cortical and seven deep or lacunar stroke patients on day 3 or 4 and day 10 post-stroke. Urinary 6-SMT and creatinine measured every 4 h for 24 h starting at 06:00 h significantly fluctuated during the day in both types of stroke and did not differ between day 3 or 4 and day 10 post-stroke. However, in extensive cortical lesions, a… CONTINUE READING