Melatonin reduces lipid peroxidation and membrane viscosity
@article{Reiter2014MelatoninRL, title={Melatonin reduces lipid peroxidation and membrane viscosity}, author={R. Reiter and D. Tan and A. Galano}, journal={Frontiers in Physiology}, year={2014}, volume={5} }
Lipid peroxidation (LPO) occurs as a result of the oxidative deterioration of polyunsaturated fatty acids (PUFA), i.e., those that contain two or more carbon–carbon double bonds. The most apparent feature of the oxidative breakdown of lipids is rancidity, a problem that was recognized centuries ago during the storage of fats and oils. Rancidity persists as a widespread problem in today's society because of the common use of polyunsaturated fats and oils.
The outer limiting membrane of cells… Expand
Figures and Topics from this paper
79 Citations
Mitochondrial bioenergetics decay in aging: beneficial effect of melatonin
- Biology, Medicine
- Cellular and Molecular Life Sciences
- 2017
- 33
Protective role of melatonin in mitochondrial dysfunction and related disorders
- Biology, Medicine
- Archives of Toxicology
- 2015
- 56
- Highly Influenced
Melatonin as an antioxidant: under promises but over delivers
- Medicine, Biology
- Journal of pineal research
- 2016
- 615
- PDF
Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics
- Biology, Medicine
- International journal of molecular sciences
- 2016
- 151
- PDF
A review of the protective role of melatonin during phosphine‐induced cardiotoxicity: focus on mitochondrial dysfunction, oxidative stress and apoptosis
- Biology, Medicine
- The Journal of pharmacy and pharmacology
- 2017
- 40
Melatonin as a mitochondria-targeted antioxidant: one of evolution’s best ideas
- Biology, Medicine
- Cellular and Molecular Life Sciences
- 2017
- 192
Molecular Mechanisms of Melatonin-Mediated Cell Protection and Signaling in Health and Disease
- Medicine
- Pharmaceutics
- 2021
- PDF
Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism
- Biology, Medicine
- Molecules
- 2015
- 225
- PDF
References
SHOWING 1-10 OF 33 REFERENCES
Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review
- Biology, Medicine
- Journal of pineal research
- 2014
- 273
Melatonin protects PLPC liposomes and LDL towards radical‐induced oxidation
- Chemistry, Biology
- Journal of pineal research
- 2011
- 20
Melatonin directly scavenges free radicals generated in red blood cells and a cell-free system: chemiluminescence measurements and theoretical calculations.
- Chemistry, Medicine
- Life sciences
- 2006
- 77
Augmentation of indices of oxidative damage in life-long melatonin-deficient rats
- Chemistry, Medicine
- Mechanisms of Ageing and Development
- 1999
- 173
Cyclic-3-hydroxymelatonin (C3HOM), a potent antioxidant, scavenges free radicals and suppresses oxidative reactions.
- Chemistry, Medicine
- Current medicinal chemistry
- 2014
- 55
Interactions of melatonin with membrane models: Portioning of melatonin in AOT and lecithin reversed micelles
- Chemistry, Medicine
- Journal of pineal research
- 1999
- 102
Evaluation of the antioxidant activity of melatonin in vitro.
- Chemistry, Medicine
- Free radical biology & medicine
- 1996
- 329
Regulation of antioxidant enzymes: a significant role for melatonin
- Biology, Medicine
- Journal of pineal research
- 2004
- 1,651
- PDF
Quantification of the water/lipid affinity of melatonin and a pinoline derivative in lipid models
- Chemistry, Medicine
- Journal of pineal research
- 2007
- 15
On the direct scavenging activity of melatonin towards hydroxyl and a series of peroxyl radicals.
- Chemistry, Medicine
- Physical chemistry chemical physics : PCCP
- 2011
- 112
- PDF