Melatonin reduces dopamine content in the neurointermediate lobe of male Syrian hamsters.

@article{Alexiuk1993MelatoninRD,
  title={Melatonin reduces dopamine content in the neurointermediate lobe of male Syrian hamsters.},
  author={N. A. M. Alexiuk and Jerry Vriend},
  journal={Brain research bulletin},
  year={1993},
  volume={32 4},
  pages={433-6}
}
The effect of daily late afternoon administration of melatonin on the in situ activity of tyrosine hydroxylase (TH) was studied in the posterior pituitary (neurointermediate lobe) of the male Syrian hamster. After 3 weeks of melatonin administration, TH activity was significantly reduced in the posterior pituitary. This was associated with a significant decrease in norepinephrine (NE) content. After 5 weeks, TH activity and NE content were no longer significantly different from controls… CONTINUE READING
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