Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas.

@article{MuozCasares2006MelatoninRA,
  title={Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas.},
  author={Francisco Crist{\'o}bal Mu{\~n}oz-Casares and Francisco Padillo and Javier Brice{\~n}o and Juan Antonio Collado and Juan R Mu{\~n}oz-Casta{\~n}eda and Rosa Ortega and Adolfo Cruz and Isaac T{\'u}nez and Pedro Montilla and Carlos Pera and Jordi Muntan{\'e}},
  journal={Journal of pineal research},
  year={2006},
  volume={40 3},
  pages={195-203}
}
The pancreas is highly susceptible to the oxidative stress induced by ischemia/reperfusion (IR) injury leading to the generation of acute pancreatitis. Melatonin has been shown to be useful in the prevention of the damage by ischemia-reperfusion in liver, brain, myocardium, gut and kidney. The aim of the study was to evaluate the cytoprotective properties of melatonin against injury induced by IR in pancreas. The obstruction of gastro-duodenal and inferior splenic arteries induced pancreatic IR… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 40 extracted citations

Similar Papers

Loading similar papers…