Melatonin receptor signaling in pregnant and nonpregnant rat uterine myocytes as probed by large conductance Ca2+-activated K+ channel activity.

@article{Steffens2003MelatoninRS,
  title={Melatonin receptor signaling in pregnant and nonpregnant rat uterine myocytes as probed by large conductance Ca2+-activated K+ channel activity.},
  author={Frank Steffens and Xiao-Bo Zhou and Ulrike Sausbier and Claudia Sailer and Karin Motejlek and Peter J. van Ruth and James Olcese and Michael Korth and Thomas Wieland},
  journal={Molecular endocrinology},
  year={2003},
  volume={17 10},
  pages={2103-15}
}
The mRNAs of MT1 and MT2 melatonin receptors are present in cells from nonpregnant (NPM) and pregnant (PM) rat myometrium. To investigate the coupling of melatonin receptors to Gq- and Gi-type of heterotrimeric G proteins, we analyzed the activity of large-conductance Ca2+-activated K+ (BKCa) channels, the expression of which in the uterus is confined to… CONTINUE READING