Melatonin prevents formaldehyde-induced neurotoxicity in prefrontal cortex of rats: an immunohistochemical and biochemical study.

@article{Zararsiz2007MelatoninPF,
  title={Melatonin prevents formaldehyde-induced neurotoxicity in prefrontal cortex of rats: an immunohistochemical and biochemical study.},
  author={Ismail Zararsiz and Ilter Kuş and Murat Ogeturk and Nusret Akpolat and Evren Kose and Sedat Meydan and Mustafa Sarsilmaz},
  journal={Cell biochemistry and function},
  year={2007},
  volume={25 4},
  pages={413-8}
}
This study was undertaken to investigate the protective effects of melatonin against formaldehyde-induced neurotoxicity in prefrontal cortex of rats. For this purpose, 21 male Wistar rats were divided into three groups. The rats in Group I were used as a control, while the rats in Group II were injected every other day with formaldehyde. The rats in Group III received melatonin daily while exposed to formaldehyde. At the end of 14-day experimental period, all rats were killed by decapitation… CONTINUE READING