Melatonin is able to prevent the liver of old castrated female rats from oxidative and pro-inflammatory damage.

@article{Kireev2008MelatoninIA,
  title={Melatonin is able to prevent the liver of old castrated female rats from oxidative and pro-inflammatory damage.},
  author={Roman A. Kireev and A. C. F. Tresguerres and Carmen Fagoaga Garc{\'i}a and Carmen Ariznavarreta and Elena Vara and Jes{\'u}s A. F. Tresguerres},
  journal={Journal of pineal research},
  year={2008},
  volume={45 4},
  pages={394-402}
}
The aim of this study was to investigate the effect of aging and ovariectomy on various physiological parameters related to inflammation and oxidative stress in livers obtained from old female rats, and the influence of chronic administration of melatonin on these animals. Twenty-four female Wistar rats of 22 months of age were used. Animals were divided into four experimental groups: two intact groups that were untreated or given melatonin (1 mg/kg/day), and two ovariectomized groups that also… CONTINUE READING
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Effect of chronic treatments with GH, melatonin, estrogens and phytoestrogens on oxidative stress parameters in liver from old age female rats

  • RA Kireev, ACF Tresguerres, C Ariznavarreta
  • Biogerontology
  • 2007
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