Melatonin improves ultraviolet B‐induced oxidative damage and inflammatory conditions in cutaneous tissue of a diurnal Indian palm squirrel Funambulus pennanti

@article{Goswami2014MelatoninIU,
  title={Melatonin improves ultraviolet B‐induced oxidative damage and inflammatory conditions in cutaneous tissue of a diurnal Indian palm squirrel Funambulus pennanti},
  author={S. Goswami and C. Haldar},
  journal={British Journal of Dermatology},
  year={2014},
  volume={171}
}
Skin is exposed to various abiotic and biotic factors. Solar radiation, of which ultraviolet (UV) rays are a principle component, increases the free radical load, and the accumulation of reactive oxygen species (ROS) causes lipid peroxidation, DNA damage and apoptosis, and is also associated with inflammatory responses recruiting molecules [nuclear factor (NF)‐κB, interleukin (IL)‐6] that can potentially further aggravate the damaged milieu of the cells. One of the potent causes of skin cancers… Expand
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