Melatonin enhances horizontal cell sensitivity in salamander retina.

  title={Melatonin enhances horizontal cell sensitivity in salamander retina.},
  author={Allan F. Wiechmann and Xiong Li Yang and S. M. Wu and Joe G. Hollyfield},
  journal={Brain research},
  volume={453 1-2},
Intracellular electrophysiological recording techniques were utilized to investigate the possible function of retinal melatonin in the larval tiger salamander. Endogenous retinal melatonin was present and appeared to bind a membrane-enriched fraction of the salamander retina, as determined by radioimmunoassay and receptor binding studies. Melatonin added through the perfusion bath to flat-mounted retinas resulted in a horizontal cell (HC) hyperpolarization of 10-20 mV. Additionally, the… CONTINUE READING

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