Corpus ID: 148570

Melatonin decreases homocysteine level in blood of rats.

@article{MurawskaCiaowicz2008MelatoninDH,
  title={Melatonin decreases homocysteine level in blood of rats.},
  author={E. Murawska-Ciałowicz and L. Januszewska and J. Zuwała-Jagiełło and J. Milczarska and M. Zawadzki and M. Paprocka-Borowicz and I. Wierzbicka-Damska},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={2008},
  volume={59 4},
  pages={
          717-29
        }
}
Elevated plasma homocysteine level promotes atherosclerosis in blood vessels due to, among others, generation of reactive oxygen species and reduction of nitric oxide bioavailability. The aim of this study was to investigate whether melatonin administration reduces plasma homocysteine level in rats consuming increased doses of methionine in the diet. The trial lasted for two months. The rats were divided into a few groups - 2 groups consisted of animals fed a standard diet, 2 groups consisted… Expand
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