Melatonin attenuates neuronal NADPH-d/NOS expression in the hypoglossal nucleus of adult rats following peripheral nerve injury

@article{Chang2000MelatoninAN,
  title={Melatonin attenuates neuronal NADPH-d/NOS expression in the hypoglossal nucleus of adult rats following peripheral nerve injury},
  author={Hung-Ming Chang and E. Ling and J. Lue and C. Wen and J. Shieh},
  journal={Brain Research},
  year={2000},
  volume={873},
  pages={243-251}
}
Oxidative stress and massive production of nitric oxide (NO) have been implicated in the neuropathogenesis following peripheral nerve injury. This study was aimed to ascertain whether melatonin would exert its neuroprotective effect on the lesioned hypoglossal neurons after peripheral axotomy, since it is known to reduce the oxidative damage in a variety of experimental neuropathologies in which NO is involved. Right-sided hypoglossal nerve transection was performed in adult rats following… Expand
Melatonin attenuates the neuronal NADPH‐d/NOS expression in the nodose ganglion of acute hypoxic rats
Melatonin preserves superoxide dismutase activity in hypoglossal motoneurons of adult rats following peripheral nerve injury
Melatonin restores the cytochrome oxidase reactivity in the nodose ganglia of acute hypoxic rats
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