Melatonin attenuates TGFβ1-induced epithelial-mesenchymal transition in lung alveolar epithelial cells.

@article{Yu2016MelatoninAT,
  title={Melatonin attenuates TGFβ1-induced epithelial-mesenchymal transition in lung alveolar epithelial cells.},
  author={Na Yu and Yi-Tian Sun and Xin-ming Su and Miao He and Bing Rong Dai and Jian Kang},
  journal={Molecular medicine reports},
  year={2016},
  volume={14 6},
  pages={5567-5572}
}
Idiopathic pulmonary fibrosis (IPF) is the most common interstitial lung disease. However, the pathogenesis remains to be fully elucidated. Melatonin is secreted by the pineal gland, it has a strong antioxidant effect, and exerts an anti-fibrosis effect. Whether melatonin attenuates pulm -onary fibrosis by inhibiting epithelial‑mesenchymal transition (EMT… CONTINUE READING