Melatonin as an Anti-Inflammatory Agent Modulating Inflammasome Activation

@inproceedings{Rezzani2017MelatoninAA,
  title={Melatonin as an Anti-Inflammatory Agent Modulating Inflammasome Activation},
  author={Rita Rezzani and Lorenzo Franceschetti and Francesca Bonomini and Luigi Fabrizio Rodella},
  booktitle={International journal of endocrinology},
  year={2017}
}
Inflammation may be defined as the innate response to harmful stimuli such as pathogens, injury, and metabolic stress; its ultimate function is to restore the physiological homeostatic state. The exact aetiology leading to the development of inflammation is not known, but a combination of genetic, epigenetic, and environmental factors seems to play an important role in the pathogenesis of many inflammation-related clinical conditions. Recent studies suggest that the pathogenesis of different… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Promising Antineoplastic Actions of Melatonin

Front. Pharmacol. • 2018
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 184 references

Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome.

Journal of pineal research • 2017
View 7 Excerpts
Highly Influenced

Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 2015
View 4 Excerpts
Highly Influenced

A Review of Melatonin, Its Receptors and Drugs.

The Eurasian journal of medicine • 2016
View 6 Excerpts
Highly Influenced

Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome.

Journal of pineal research • 2016
View 6 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…