Melatonin as a potential antihypertensive treatment.

  title={Melatonin as a potential antihypertensive treatment.},
  author={Fedor Simko and Ludovit Paulis},
  journal={Journal of pineal research},
  volume={42 4},
The number of patients with well-controlled hypertension is alarmingly low worldwide and new approaches to treatment of increased blood pressure (BP) are being sought. Melatonin has a role in blood pressure regulation. The nighttime production of melatonin is found to be reduced in hypertensive individuals. Administration of melatonin decreased BP in several animal models of hypertension, in healthy men and women, and in patients with arterial hypertension. Most promising results were achieved… CONTINUE READING


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