Melatonin and human rhythms.

@article{Arendt2006MelatoninAH,
  title={Melatonin and human rhythms.},
  author={Jos{\'e}phine Arendt},
  journal={Chronobiology international},
  year={2006},
  volume={23 1-2},
  pages={
          21-37
        }
}
Melatonin signals time of day and time of year in mammals by virtue of its pattern of secretion, which defines 'biological night.' It is supremely important for research on the physiology and pathology of the human biological clock. Light suppresses melatonin secretion at night using pathways involved in circadian photoreception. The melatonin rhythm (as evidenced by its profile in plasma, saliva, or its major metabolite, 6-sulphatoxymelatonin [aMT6s] in urine) is the best peripheral index of… CONTINUE READING

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