Corpus ID: 3133036

Melatonin and Sleep

@article{Zisapel2010MelatoninAS,
  title={Melatonin and Sleep},
  author={N. Zisapel},
  journal={The Open Neuroendocrinology Journal},
  year={2010},
  volume={3}
}
  • N. Zisapel
  • Published 2010
  • Psychology
  • The Open Neuroendocrinology Journal
  • Melatonin is produced over the night in a process driven by the circadian clock that resides in the suprachiasmatic nuclei (SCN), and by ambient light. It is a time cue to tune the sleep-wake and other circadian rhythms with the day-night cycles and thus useful in circadian rhythm sleep disorders. In addition melatonin induces fatigue and concurrent sleep-like changes in brain activation patterns in humans. With age SCN activity and melatonin production capacity decline thus depriving the brain… CONTINUE READING
    18 Citations
    New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation
    • N. Zisapel
    • Medicine
    • British journal of pharmacology
    • 2018
    • 96
    Potential safety issues in the use of the hormone melatonin in paediatrics
    • D. Kennaway
    • Medicine
    • Journal of paediatrics and child health
    • 2015
    • 43
    Sleeping Disturbances
    Running head : SLEEPING DISTURBANCES 1 Sleeping Disturbances
    Jerte Valley cherry-enriched diets improve nocturnal rest and increase 6-sulfatoxymelatonin and total antioxidant capacity in the urine of middle-aged and elderly humans.
    • 93
    • PDF

    References

    SHOWING 1-10 OF 141 REFERENCES
    Circadian Rhythm Sleep Disorders
    • 135
    Melatonin stabilises sleep onset time in a blind man without entrainment of cortisol or temperature rhythms
    • 156
    Integration of human sleep-wake regulation and circadian rhythmicity.
    • 312
    • PDF
    Role of Melatonin in the Regulation of Human Circadian Rhythms and Sleep
    • 479
    • PDF
    Sleep and sleep disturbances: biological basis and clinical implications
    • N. Zisapel
    • Biology, Medicine
    • Cellular and Molecular Life Sciences
    • 2007
    • 159
    Sleep-anticipating effects of melatonin in the human brain
    • 58
    Melatonin in Circadian Sleep Disorders in the Blind
    • 63
    Improvement of sleep quality in elderly people by controlled-release melatonin
    • 455
    • PDF