Corpus ID: 3133036

Melatonin and Sleep

  title={Melatonin and Sleep},
  author={N. Zisapel},
  journal={The Open Neuroendocrinology Journal},
  • N. Zisapel
  • Published 2010
  • Psychology
  • The Open Neuroendocrinology Journal
  • Melatonin is produced over the night in a process driven by the circadian clock that resides in the suprachiasmatic nuclei (SCN), and by ambient light. It is a time cue to tune the sleep-wake and other circadian rhythms with the day-night cycles and thus useful in circadian rhythm sleep disorders. In addition melatonin induces fatigue and concurrent sleep-like changes in brain activation patterns in humans. With age SCN activity and melatonin production capacity decline thus depriving the brain… CONTINUE READING
    18 Citations
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    Sleep and sleep disturbances: biological basis and clinical implications
    • N. Zisapel
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    • Cellular and Molecular Life Sciences
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    • 159
    Sleep-anticipating effects of melatonin in the human brain
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    Melatonin in Circadian Sleep Disorders in the Blind
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    Improvement of sleep quality in elderly people by controlled-release melatonin
    • 455
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