Melatonin administration alters semen quality in healthy men.

@article{Luboshitzky2002MelatoninAA,
  title={Melatonin administration alters semen quality in healthy men.},
  author={Rafael Luboshitzky and Z Shen-Orr and Rachel Nave and Schahar Lavi and Peretz Lavie},
  journal={Journal of andrology},
  year={2002},
  volume={23 4},
  pages={
          572-8
        }
}
The role of melatonin in the regulation of reproduction in humans is unknown. We conducted a 6-month, double-blind, crossover study of a daily treatment dose of 3 mg melatonin or placebo given orally at 1700 hours in 8 healthy men. Semen quality (concentration, motility, and morphology), serum and seminal plasma 17-beta-estradiol (E(2)), testosterone, melatonin, and serum gonadotropin levels were determined every 3 months throughout the study. In 6 men, there was no change in semen quality or… CONTINUE READING

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