Melatonin Treatment for Insomnia in Pediatric Patients with Attention-Deficit/Hyperactivity Disorder

@article{Bendz2010MelatoninTF,
  title={Melatonin Treatment for Insomnia in Pediatric Patients with Attention-Deficit/Hyperactivity Disorder},
  author={Lisa M Bendz and Ann C Scates},
  journal={Annals of Pharmacotherapy},
  year={2010},
  volume={44},
  pages={185 - 191}
}
OBJECTIVE To evaluate the efficacy and safety of melatonin for the treatment of insomnia in pediatric patients with attention-deficit/hyperactivity disorder (ADHD). DATA SOURCES Literature was accessed through MEDLINE (1948-August 2009), EMBASE (1950-August 2009), and Scopus (1960-August 2009) using the terms melatonin, attention-deficit/hyperactivity disorder (ADHD), pediatric, insomnia, sleep disorder, and sleep. In addition, reference citations from publications identified were reviewed for… Expand
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  • Medicine
  • Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
  • 2017
TLDR
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References

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Sleep hygiene and melatonin treatment for children and adolescents with ADHD and initial insomnia.
TLDR
Combined sleep hygiene and melatonin was a safe and effective treatment for initial insomnia in children with ADHD taking stimulant medication. Expand
Sleep in children with attention-deficit hyperactivity disorder (ADHD): a review of naturalistic and stimulant intervention studies.
TLDR
The main objectives of this review were to provide pediatric clinicians and researchers a clear and concise summary of published sleep data in children with ADHD, to provide a more accurate description of the current knowledge of the relationship between sleep and ADHD, and to provide current information on the effect of stimulant medication on sleep. Expand
Long‐term follow‐up of melatonin treatment in children with ADHD and chronic sleep onset insomnia
TLDR
It is concluded that melatonin remains an effective therapy on the long term for the treatment of CSOI in children with ADHD and has no safety concerns regarding serious adverse events or treatment related co‐morbidity. Expand
Effect of melatonin on sleep, behavior, and cognition in ADHD and chronic sleep-onset insomnia.
TLDR
Melatonin advanced circadian rhythms of sleep-wake and endogenous melatonin and enhanced total time asleep in children with ADHD and chronic sleep onset insomnia; however, no effect was found on problem behavior, cognitive performance, or quality of life. Expand
Melatonin for treatment of sleeping disorders in children with attention deficit/hyperactivity disorder: a preliminary open label study
A dose of 3 mg melatonine reduces the time of falling asleep significantly in attention deficit/hyperactivity disorder (ADHD) subjects on methylphenidate treatment. Insomnia occurs in up to 54% inExpand
Pharmacological management of treatment-induced insomnia in ADHD.
ADHD AND INSOMNIA VIGNETTE A 7-year-old girl with attention-deficit/hyperactivity disorder (ADHD), combined subtype, and oppositional defiant disorder presents with a complaint of marked insomnia.Expand
Sleep disturbances in children with attention-deficit/hyperactivity disorder.
TLDR
Empirical research published since 1970 on sleep disturbances in children with ADHD was systematically reviewed and a "box-score" approach was used to examine consistency of findings across the studies, which used different outcome measures. Expand
Clinical trials of controlled‐release melatonin in children with sleep–wake cycle disorders
TLDR
The studies showed that the FR melatonin was most effective when there was only delayed sleep onset, but CR formulations were more useful for sleep maintenance, and children appeared to require higher doses than adults. Expand
Melatonin for Chronic Sleep Onset Insomnia in Children: A Randomized Placebo-Controlled Trial
TLDR
The results show that melatonin, 5 mg at 6 PM, was relatively safe to take in the short term and significantly more effective than placebo in advancing sleep onset and dim light melatonin onset and increasing sleep duration in elementary school children with chronic sleep onset insomnia. Expand
Pharmacologic Management of Insomnia in Children and Adolescents: Consensus Statement
TLDR
A consensus statement on the current status and future role for pharmacologic management of insomnia in children and adolescents was developed and priority should be given to insomnia studies in children with attention-deficit/hyperactivity disorder and those with pervasive developmental disorders/autism spectrum disorder. Expand
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