Melatonin Receptor Genes in Vertebrates

  title={Melatonin Receptor Genes in Vertebrates},
  author={Di Yan Li and David G. Smith and R{\"u}diger Hardeland and Ming Yao Yang and Huai Liang Xu and Long Zhang and Hua Dong Yin and Qing Zhu},
  booktitle={International journal of molecular sciences},
Melatonin receptors are members of the G protein-coupled receptor (GPCR) family. Three genes for melatonin receptors have been cloned. The MT1 (or Mel1a or MTNR1A) and MT2 (or Mel1b or MTNR1B) receptor subtypes are present in humans and other mammals, while an additional melatonin receptor subtype, Mel1c (or MTNR1C), has been identified in fish, amphibians and birds. Another melatonin related orphan receptor, GPR50, which does not bind melatonin, is found exclusively in mammals. The hormone… CONTINUE READING

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