Melatonin: comprehensive profile.

@article{AlOmary2013MelatoninCP,
  title={Melatonin: comprehensive profile.},
  author={Fatmah A. M. Al-Omary},
  journal={Profiles of drug substances, excipients, and related methodology},
  year={2013},
  volume={38},
  pages={
          159-226
        }
}
  • Fatmah A. M. Al-Omary
  • Published 2013
  • Chemistry, Medicine
  • Profiles of drug substances, excipients, and related methodology
This chapter includes the aspects of melatonin. The drug is synthesized in the pineal gland starting from tryptophane or synthetically by using indole as starting material. Melatonin has been used as an adjunct to interleukin-2 therapy for malignant neoplasms, as contraceptive, in the management of various forms of insomnia, to alleviate jet lag following long flights, and finally as free radical scavenger and hence as an antioxidant and an anti-inflammatory. The chapter discusses the drug… Expand
22 Citations

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