Melatonin, an ubiquitous metabolic regulator: functions, mechanisms and effects on circadian disruption and degenerative diseases

@article{Socaciu2020MelatoninAU,
  title={Melatonin, an ubiquitous metabolic regulator: functions, mechanisms and effects on circadian disruption and degenerative diseases},
  author={Andreea Iulia Socaciu and Răzvan Ionuţ and Mihai Adrian Socaciu and Andreea Petra Ungur and Maria B{\^a}rsan and Angelica Chiorean and Carmen Socaciu and Armand Gabriel R{\^a}jnoveanu},
  journal={Reviews in Endocrine and Metabolic Disorders},
  year={2020},
  volume={21},
  pages={465 - 478}
}
The last four decades, we assist to an increasing scientific interest on melatonin, a circadian hormone, a metabolic regulator which influences not only plants’ metabolism and their defense against pathogens but mostly the animals and humans’ metabolic pathways, their response to circadian disruption, stress and burnout syndrome. In humans, as a hormonal regulator, produced in the pineal grand as well in mitochondria, melatonin is involved in different, complex intracellular signaling pathways… 
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