Melasma: systematic review of the systemic treatments

@article{Zhou2017MelasmaSR,
  title={Melasma: systematic review of the systemic treatments},
  author={Linghong Linda Zhou and Akerke T Baibergenova},
  journal={International Journal of Dermatology},
  year={2017},
  volume={56}
}
Currently available treatment options for melasma include prevention of UV radiation, topical lightening agents, chemical peels, and light‐based and laser therapies. However, none have shown effective and sustained results, with incomplete clearance and frequent recurrences. There has been increasing interest recently in oral medications and dietary supplements in improving melasma. We sought to evaluate the efficacy and safety/tolerability of oral medications and dietary supplements for the… 

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