Corpus ID: 31365968

Melanosis coli

  title={Melanosis coli},
  author={Siang-Tong Kew},
  • Siang-Tong Kew
  • Published 2012
  • Melanosis coli denotes brownish discoloration of the colonic mucosa found on endoscopy or histopathologic examination. The condition has no specific symptom on its own. It is a fairly frequent incidental finding of colonic biopsies and resection specimens. The pigmentation is caused by apoptotic cells which are ingested by macrophages and subsequently transported into the lamina propria, where lysosomes use them to produce lipofuscin pigment, not melanin as the name suggests. Melanosis coli… CONTINUE READING
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