Melanopsin Tristability for Sustained and Broadband Phototransduction

@article{Emanuel2015MelanopsinTF,
  title={Melanopsin Tristability for Sustained and Broadband Phototransduction},
  author={Alan Joseph Emanuel and Michael Tri H Do},
  journal={Neuron},
  year={2015},
  volume={85},
  pages={1043-1055}
}
Mammals rely upon three ocular photoreceptors to sense light: rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs). Rods and cones resolve details in the visual scene. Conversely, ipRGCs integrate over time and space, primarily to support "non-image" vision. The integrative mechanisms of ipRGCs are enigmatic, particularly since these cells use a phototransduction motif that allows invertebrates like Drosophila to parse light with exceptional temporal resolution. Here… CONTINUE READING
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