Melanoma inhibitor of apoptosis protein is expressed differentially in melanoma and melanocytic naevus, but similarly in primary and metastatic melanomas.

@article{Gong2005MelanomaIO,
  title={Melanoma inhibitor of apoptosis protein is expressed differentially in melanoma and melanocytic naevus, but similarly in primary and metastatic melanomas.},
  author={Jing Gong and Ni Chen and Q Zhou and Bo Yang and Yuhui Wang and Xudong Wang},
  journal={Journal of clinical pathology},
  year={2005},
  volume={58 10},
  pages={1081-5}
}
BACKGROUND Malignant melanoma is highly resistant to current treatments. The inhibitor of apoptosis protein (IAP) family member, melanoma IAP (ML-IAP), is overexpressed in some melanoma cell lines, rendering them resistant to apoptotic signals. Targeting ML-IAP is a promising approach to treating melanoma. However, the status of ML-IAP expression in human melanoma tissues and the difference in expression between melanoma and melanocytic naevus are not known. AIMS To investigate these issues… CONTINUE READING