Melanoma cell attachment, invasion, and integrin expression is upregulated by tumor necrosis factor alpha and suppressed by alpha melanocyte stimulating hormone.

@article{Zhu2002MelanomaCA,
  title={Melanoma cell attachment, invasion, and integrin expression is upregulated by tumor necrosis factor alpha and suppressed by alpha melanocyte stimulating hormone.},
  author={Ningwen Zhu and Paula Clare Eves and Effie Katerinaki and Marika J Szabo and Renato Morandini and Ghanem E. Ghanem and Paul C. Lorigan and Sheila MacNeil and John W Haycock},
  journal={The Journal of investigative dermatology},
  year={2002},
  volume={119 5},
  pages={1165-71}
}
We have previously shown alpha-melanocyte stimulating hormone to protect melanocytes and melanoma cells from the proinflammatory actions of tumor necrosis factor-alpha. The aim of the study was to extend this work to look into the influence of tumor necrosis factor-alpha on melanoma cell attachment, invasion, and integrin expression and ask to what extent alpha-melanocyte stimulating hormone might protect cells from tumor necrosis factor-alpha stimulation of increased integrin expression. HBL… CONTINUE READING

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