Melanogenesis inhibitory and fibroblast proliferation accelerating effects of noroleanane- and oleanane-type triterpene oligoglycosides from the flower buds of Camellia japonica.

@article{Nakamura2012MelanogenesisIA,
  title={Melanogenesis inhibitory and fibroblast proliferation accelerating effects of noroleanane- and oleanane-type triterpene oligoglycosides from the flower buds of Camellia japonica.},
  author={Seikou Nakamura and T Moriura and Sunmi Park and Katsuyoshi Fujimoto and Takahiro Matsumoto and Tomoe Ohta and Hisashi Matsuda and Masayuki Yoshikawa},
  journal={Journal of natural products},
  year={2012},
  volume={75 8},
  pages={
          1425-30
        }
}
A 28-noroleanane-type triterpene oligoglycoside, camellioside E (4), an oleanane-type triterpene oligoglycoside, camellioside F (5), and the known compounds camelliosides A (1) and D (3) were isolated from a 50% EtOH extract of Camellia japonica flower buds from Korea. The principal constituents (1 and 5) significantly inhibited melanogenesis in theophylline-stimulated B16 melanoma 4A5 cells. Camellioside B (2), a major constituent of C. japonica grown in Japan, showed potent inhibition of… 
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