Melanogenesis and Antityrosinase Activity of Selected South African Plants

@article{Mapunya2012MelanogenesisAA,
  title={Melanogenesis and Antityrosinase Activity of Selected South African Plants},
  author={Manyatja Brenda Mapunya and Roumiana Vassileva Nikolova and Namrita Lall},
  journal={Evidence-based Complementary and Alternative Medicine : eCAM},
  year={2012},
  volume={2012}
}
Melanin is the pigment that is responsible for the colour of eyes, hair, and skin in humans. Tyrosinase is known to be the key enzyme in melanin biosynthesis. Overactivity of this enzyme leads to dermatological disorders such as age spots, melanoma and sites of actinic damage. Ten plants belonging to four families (Asphodelaceae, Anacardiaceae, Oleaceae, and Rutaceae) were investigated for their effect on tyrosinase using both L-tyrosine and L-DOPA as substrates. Ethanol leaf extracts (500 μg… Expand
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