Melanocyte movement in vitro: role of matrix proteins and integrin receptors.

  title={Melanocyte movement in vitro: role of matrix proteins and integrin receptors.},
  author={Joseph G. Morelli and J J Yohn and T Zekman and David A. Norris},
  journal={The Journal of investigative dermatology},
  volume={101 4},
During the repigmentation of vitiliginous skin, melanocytes migrate from the outer root sheath of the hair follicle into the depigmented skin. We hypothesize that this requires changes in the local microenvironment that are conductive to melanocyte migration. One important change in the microenvironment could be the localized production of matrix proteins. We have previously employed time-lapse photography to evaluate the effect of inflammatory mediators and cytokines on melanocyte movement. We… CONTINUE READING

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